Fever, cold and flu-related aches and pains, headaches, backaches, rheumatic and muscle pains, period pains, and toothaches can all be quickly and effectively relieved with Panadol Night pills. The ingredients in Panadol Night tablets include diphenhydramine hydrochloride, an antihistamine that helps people sleep soundly and relieves cold and flu symptoms like congestion, as well as paracetamol, an analgesic (a pain reliever that relieves aches and pains) and antipyretic (it lowers body temperature when you have a fever).